Cyclic RGDFK peptide

CAS No.	161552-03-0	Cat. No.	BCP07356
Name	Cyclic RGDFK peptide
Synonyms	RGDFK; ARG-GLY-ASP-D-PHE-LYS; Cyclo (-RGDfK);
Formula	C27H41N9O7	M. Wt	603.67

Description	In one study where this peptide was labeled with 125I, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. The integrin alpha(IIb)beta(3)-specific cyclic hexapeptide contains an Arg-Gly-Asp (RGD) sequence.
Pathways	Angiogenesis/Protein Tyrosine Kinase
Targets	Integrin

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