INNO-206 HCl

CAS No.	480998-12-7	Cat. No.	BCP07339
Name	INNO-206 HCl
Synonyms	MC-DOXHZN hydrochloride;INNO-206 monohydrochloride; INNO206 HCl salt; Aldoxorubicin HCl;
Formula	C37H42N4O13.HCl	M. Wt	787.21

Description	Aldoxorubicin, also known as INNO-206, is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity. Following intravenous administration, doxorubicin prodrug INNO-206 binds selectively to the cysteine-34 position of albumin via its maleimide moiety. Doxorubicin is released from the albumin carrier after cleavage of the acid-sensitive hydrazone linker within the acidic environment of tumors and, once located intracel
Pathways	Cell Cycle/DNA Damage Others Pathway
Targets	Topoisomerase ADC Related

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