L-甲状腺素钠

  • 化学数据
CAS号 25416-65-3 货号 BCP07321
中文名 L-甲状腺素钠
英文名 Sodium levothyroxine
中文别名
英文别名 Levothyroxine sodium;L-Thyroxine sodium;
分子式 C15H10I4NNaO4 分子量 798.85
  • 用途
生物活性 Levothyroxine Sodium is the sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration; thermogenesis; cellular growth and differentiation; and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects.
信号通路 Hormone Pathay 
靶 点 Thyroid Hormone Receptor 

结构式

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