L-甲状腺素钠
CAS号 | 25416-65-3 | 货号 | BCP07321 |
中文名 | L-甲状腺素钠 | ||
英文名 | Sodium levothyroxine | ||
中文别名 | |||
英文别名 | Levothyroxine sodium;L-Thyroxine sodium; | ||
分子式 | C15H10I4NNaO4 | 分子量 | 798.85 |
生物活性 | Levothyroxine Sodium is the sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration; thermogenesis; cellular growth and differentiation; and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects. | ||
信号通路 | Hormone Pathay | ||
靶 点 | Thyroid Hormone Receptor |
结构式
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