鱼滕酮
CAS号 | 83-79-4 | 货号 | BCP07278 |
中文名 | 鱼滕酮 | ||
英文名 | Rotenone | ||
中文别名 | |||
英文别名 | Cube root; bCube-Pulver; Ronone; HSDB 1762; Ro-KO; | ||
分子式 | C23H22O6 | 分子量 | 394.42 |
生物活性 | Rotenone is a botanical insecticide that is an inhibitor of mitochondrial electron transport. which specifically inhibits NAD-linked substrate oxidation of NADH dehydrogenase with an EC50=10 pmol/mg. It is known that this interference of the electron transport chain occurs from complex I to ubiquinone, similarly to amytal. Studies indicate that Rotenone inhibits mammalian cell proliferation, via suppressing microtubule assembly by binding to tubulin. Rotenone can inhibit the effects of N-methyl-4-phenylpyridinium on mitochondrial swelling and cytochrome c release. Rotenone is an inhibitor of NDUFS. | ||
信号通路 | Protease/Metabolic Enzyme | ||
靶 点 | Mitochondrial Metabolism |
结构式

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