Mifamurtide

  • Chemical Properties
CAS No. 83461-56-7 Cat. No. BCP07203
Name Mifamurtide
Synonyms CGP 19835A Lipid;CGP-19835; MTP-PE; MTP-cephalin; CGP19835; L-MTP-PE; MLV19835;
Formula C59H109N6O19P M. Wt 1237.5
  • Biological Activity
Description Mifamurtide(CGP19835; MTP-PE) is a liposomal formulation containing a muramyl dipeptide (MDP) analogue with potential immunomodulatory and antineoplastic activities.. Muramyl tripeptide phosphatidylethanolamine (MTP-PE), a derivative of the mycobacterial cell wall component MDP, activates both monocytes and macrophages. Activated macrophages secrete cytokines and induce the recruitment and activation of other immune cells, which may result in indirect tumoricidal effects. Liposomal encapsulation of MTP-PE prolongs its half-life and enhances tissue targeting. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus).
Pathways Ion Channel/Membrane Transporter 
Targets TRP Channel 

Structure

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