Tezacaftor
| CAS No. | 1152311-62-0 | Cat. No. | BCP07173 |
| Name | Tezacaftor | ||
| Synonyms | VX 661; VX661;VX-661; | ||
| Formula | C26H27F3N2O6 | M. Wt | 520.5 |
| Description | VX-661 is CFTR modulator. VX-661 is potentially useful for treatment of cystic fibrosis disease. Cystic fibrosis (CF) is a genetic disease caused by defects in the CF transmembrane regulator (CFTR) gene, which encodes an epithelial chloride channel. The most common mutation, Δ508CFTR, produces a protein that is misfolded and does not reach the cell membrane. VX-661 can correct trafficking of Δ508CFTR and partially restore chloride channel activity. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | CFTR | ||
Structure
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