WY-14643
| CAS No. | 50892-23-4 | Cat. No. | BCP21201 |
| Name | WY-14643 | ||
| Synonyms | WY 14643; WY14643; Pirinixic Acid; | ||
| Formula | C14H14ClN3O2S | M. Wt | 323.8 |
| Description | WY-14643, also known as pirinixic acid, is a selective PPARα agonist. WY-14643 negatively inhibits NF-κB transcriptional activity and decreases the inflammatory response in vitro and in vivo.Wy-14643 is a potent agonist of PPARα, with EC50s of 0.63 μM, 32 μM for murine PPARα and PPARγ, and 5.0 μM, 60 μM, 35 μM for human PPARα, PPARγ and PPARδ, respectively. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PPAR | ||
Structure
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