PF-543
| CAS No. | 1415562-82-1 | Cat. No. | BCP07072 |
| Name | PF-543 | ||
| Synonyms | PF543; PF 543;Sphingosine Kinase 1 Inhibitor II; | ||
| Formula | C27H31NO4S | M. Wt | 465.6 |
| Description | PF-543 is a novel cell-permeant inhibitor of SphK1. PF-543 inhibits SphK1 with a K(i) of 3.6 nM, is sphingosine-competitive and is more than 100-fold selective for SphK1 over the SphK2 isoform. PF-543 is the most potent inhibitor of SphK1 described to date and it will be useful for dissecting specific roles of SphK1-driven S1P signalling. | ||
| Pathways | GPCR/G Protein | ||
| Targets | S1P Receptor | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.