Duvelisib
CAS No. | 1201438-56-3 | Cat. No. | BCP07042 |
Name | Duvelisib | ||
Synonyms | IPI-145;INK1197; IPI 145; IPI145; INK-1197; INK 1197; | ||
Formula | C22H17ClN6O | M. Wt | 416.86 |
Description | Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, PI3K delta/gamma inhibitor IPI 145 prevents the activation of the PI3K delta/gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta/gamma-expressing tumor cells. Unlike other isoforms of | ||
Pathways | PI3K/Akt/mTOR | ||
Targets | PI3K |
Structure
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