A740003
| CAS No. | 861393-28-4 | Cat. No. | BCP06995 |
| Name | A740003 | ||
| Synonyms | A 740003; A740003; | ||
| Formula | C26H30N6O3 | M. Wt | 474.57 |
| Description | A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively). A-740003 displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. A-740003 reduces nociception in animal models of persistent neuropathic and inflammatory pain. | ||
| Pathways | Ion Channel/Membrane Transporter Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | P2 Receptor | ||
Structure
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