ABT492
| CAS No. | 189279-58-1 | Cat. No. | BCP21227 |
| Name | ABT492 | ||
| Synonyms | Delafloxacin; Delafloxacinum; ABT-492 ; ABT 492; | ||
| Formula | C18H12ClF3N4O4 | M. Wt | 440.76 |
| Description | ABT-492 is a new fluoroquinolone against 155 aerobic and 171 anaerobic pathogens. It exhibited excellent in vitro activities against all 326 aerobic and anaerobic antral puncture sinus isolates tested with MICs (in micrograms per milliliter) at which 90% of the isolates tested were inhibited as follows: Haemophilus influenzae, 0.001; Moraxella catarrhalis, 0.008; and Streptococcus pneumoniae, 0.015. It was four- to sixfold more active than other fluoroquinolones, including against levofloxacin-resistant strains of S. pneumoniae, methicillin-resistant Staphylococcus aureus, and Prevotella species. | ||
| Pathways | Microbiology/Virology | ||
| Targets | Antibiotic | ||
Structure
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