Exendin-4
CAS No. | 141758-74-9 | Cat. No. | BCP06982 |
Name | Exendin-4 | ||
Synonyms | Exenatide; | ||
Formula | C184H282N50O60S | M. Wt | 4186.57 |
Description | Exendin-4 stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1(glucagon-like peptide-1) receptor-dependent mechanism. Exendin-4, the long-acting GLP-1 receptor agonist, is an incretin mimetic approved for type 2 diabetes mellitus treatment. Studies also demonstrated its neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. | ||
Pathways | GPCR/G Protein | ||
Targets | Glucagon Receptor |
Structure
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