艾塞那肽
CAS号 | 141758-74-9 | 货号 | BCP06982 |
中文名 | 艾塞那肽 | ||
英文名 | Exendin-4 | ||
中文别名 | |||
英文别名 | Exenatide; | ||
分子式 | C184H282N50O60S | 分子量 | 4186.57 |
生物活性 | Exendin-4 stimulates proliferation of HCAECs through PKA-PI3K/Akt-eNOS activation pathways via a GLP-1(glucagon-like peptide-1) receptor-dependent mechanism. Exendin-4, the long-acting GLP-1 receptor agonist, is an incretin mimetic approved for type 2 diabetes mellitus treatment. Studies also demonstrated its neurotrophic/protective activity in cellular and animal models of stroke, Alzheimer's and Parkinson's diseases. | ||
信号通路 | GPCR/G Protein | ||
靶 点 | Glucagon Receptor |
结构式
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