Zotarolimus

  • Chemical Properties
CAS No. 221877-54-9 Cat. No. BCP06922
Name Zotarolimus
Synonyms A-179578; A 179578; A179578;ABT 578 ; ABT578; ABT-578; A 179578; Resolute;
Formula C52H79N5O12 M. Wt 966.21
  • Biological Activity
Description Zotarolimus, also known as ABT-578 and A-179578, is an immunosuppressant. It is a semi-synthetic derivative of rapamycin. It was designed for use in stents with phosphorylcholine as a carrier. Coronary stents reduce early complications and improve late clinical outcomes in patients needing interventional cardiology. Medtronic are using zotarolimus as the anti-proliferative agent in the polymer coating of their Endeavor and Resolute products.
Pathways Others Pathway 
Targets Others 

Structure

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