JNJ1661010
| CAS No. | 681136-29-8 | Cat. No. | BCP06935 |
| Name | JNJ1661010 | ||
| Synonyms | JNJ-1661010;JNJ 1661010; | ||
| Formula | C19H19N5OS | M. Wt | 365.46 |
| Description | FAAH preincubated with JNJ-1661010 suggests a slow reversibility of the interaction between the JNJ-1661010 and the active site, which is accelerated at higher temperatures.JNJ-1661010 is a covalent, mechanism-based substrate inhibitor as examined by LC-ESI-MS. JNJ-1661010 docks with the phenylthiadiazole in the hydrophobic tunnel and the phenylurea in the hydrophilic pocket of FAAH. | ||
| Pathways | Protease/Metabolic Enzyme Neuro Signaling Pathway | ||
| Targets | FAAH | ||
Structure
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