烟酰胺核糖

  • 化学数据
CAS号 1341-23-7 货号 BCP06938
中文名 烟酰胺核糖
英文名 Nicotinamide Riboside
中文别名
英文别名 Nicotinamide ribose; Nicotinamide-beta-riboside; SRT647; SRT-647; SRT 647;
分子式 C11H16N2O5 分子量 256.26
  • 用途
生物活性 Nicotinamide riboside is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+. NR blocks degeneration of surgically severed dorsal root ganglion neurons ex vivo and protects against noise-induced hearing loss in living mice. Nicotinamide riboside prevents muscle, neural and melanocyte stem cell senescence. Increased muscular regeneration in mice has been observed after treatment with nicotinamide riboside, leading to speculation that it might improve regeneration of organs such as the liver, kidney, and heart. Nicotinamide riboside also lowers blood glucose and fatty liver in prediabetic and type 2 diabetic models while preventing the development of diabetic peripheral neuropathy. Note: Nicotinamide Riboside chloride is a α/β mixture
  • 引用文献
Hepatic NAD+ deficiency as a therapeutic target for non‐alcoholic fatty liver disease in ageing

购于瀚香生物(Biochempartner)的烟酰胺核糖(CAS:1341-23-7)被引用

Administration of nicotinamide riboside prevents oxidative stress and organ injury in sepsis

购于瀚香生物(Biochempartner)的烟酰胺核糖(CAS:1341-23-7)被引用

结构式

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