Epothilone D

  • Chemical Properties
CAS No. 189453-10-9 Cat. No. BCP06921
Name Epothilone D
Synonyms Desoxyepothilone B;KOS 862;KOS-862;KOS862;
Formula C27H41NO5S M. Wt 491.68
  • Biological Activity
Description Intermediary obtained in the synthesis of members of the Epothilone family, polyketide natural products that inhibit cancer cells via a mechanism similar to Paclitaxel. Epothilone D also found to be effective against Paclitaxel-resistant tumors. Epothilone D currently in Phase I of clinical testing.
Pathways Cell Cycle/DNA Damage 
Targets Microtubule 

Structure

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