Mirabegron
| CAS No. | 223673-61-8 | Cat. No. | BCP06891 |
| Name | Mirabegron | ||
| Synonyms | YM 178; YM-178; YM178;Betmiga;Betanis; | ||
| Formula | C21H24N4O2S | M. Wt | 396.51 |
| Description | Mirabegron is an orally bioavailable agonist of the human beta-3 adrenergic receptor (ADRB3), with muscle relaxing, neuroprotective and potential antineoplastic activities. Upon oral administration, mirabegron binds to and activates ADRB3, which leads to smooth muscle relaxation. Mirabegron also restores sympathetic stimulation in mesenchymal stem cell (MSC) niches, inhibits JAK2-mutated hematopoietic stem cell (HSC) expansion and blocks the progression of myeloproliferative neoplasms (MPNs). Lack of sympathetic stimulation of the MSC and HSC niche is associated with the development of MPNs. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | Adrenergic Receptor | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.