LY-404187

  • Chemical Properties
CAS No. 211311-95-4 Cat. No. BCP06868
Name LY-404187
Synonyms LY404187;LY404187;
Formula C19H22N2O2S M. Wt 342.46
  • Biological Activity
Description LY-404187 is an ampakine, AMPA receptor potentiator. LY-404187 has been demonstrated to enhance cognitive function in animal studies, and has also shown effects suggesting antidepressant action as well as having possible application in the treatment of schizophrenia, Parkinson's disease and ADHD. These effects appear to be mediated through multiple mechanisms of action secondary to AMPA receptor potentiation, with a prominent effect seen in research being increased levels of BDNF in the brain.
Pathways Ion Channel/Membrane Transporter 
Targets AMPA/NMDA 

Structure

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