CID-2011756
| CAS No. | 638156-11-3 | Cat. No. | BCP06823 |
| Name | CID-2011756 | ||
| Synonyms | CID2011756; CID 2011756; | ||
| Formula | C22H21N2O3Cl | M. Wt | 396.87 |
| Description | CID-2011756 is a cell-active ATP competitive and specific PKD1 inhibitor that inhibits phorbol ester-induced endogenous PKD1 activation in LNCaP prostate cancer cells. CID 2011756, has pan-PKD inhibitory effects (PKD2 IC50 = 0.6±0.1; PKD3 IC50 = 0.7±0.2 ?M) with similar, albeit not identical, potencies which may be expected for an ATP competitive inhibitor. CID 2011756 was the most potent of the inhibitors with a cellular EC50 of 10±0.7 ?M (n = 3), an EC50 value comparable to that of our pre | ||
| Pathways | Apoptosis Pathway | ||
| Targets | PKD | ||
Structure
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