Detomidine HCl

CAS No.	90038-01-0	Cat. No.	BCP06805
Name	Detomidine HCl
Synonyms	Detomidine hydrochloride; MPV-253 HCl; MPV 253 HCl; MPV253 HCl;
Formula	C12H14N2.HCl	M. Wt	222.71

Description	Detomidine is an imidazole derivative and α2-adrenergic agonist, used as a large animal sedative, primarily used in horses. It is usually available as the salt detomidine hydrochloride. It is a prescription medication available to veterinarians sold under the trade name Dormosedan. Currently, detomidine is only licenced for use in horses. Detomidine is a sedative with analgesic properties. α2-adrenergic agonists produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	Adrenergic Receptor

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