Troglitazone

CAS No.	97322-87-7	Cat. No.	BCP06753
Name	Troglitazone
Synonyms	CS-045;CS 045;CS045;Noscal;CI-991; CI991; CI 991;GR 92132X; GR92132X;GR-92132X;
Formula	C24H27NO5S	M. Wt	441.54

Description	Troglitazone is an orally-active thiazolidinedione with antidiabetic and hepatotoxic properties and potential antineoplastic activity. Troglitazone activates peroxisome proliferator-activated receptor gamma (PPAR-gamma), a ligand-activated transcription factor, thereby inducing cell differentiation and inhibiting cell growth and angiogenesis. This agent also modulates the transcription of insulin-responsive genes, inhibits macrophage and monocyte activation, and stimulates adipocyte differentiation.
Pathways	Cell Cycle/DNA Damage
Targets	PPAR

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