Necrostatin-1

  • Chemical Properties
CAS No. 4311-88-0 Cat. No. BCP06760
Name Necrostatin-1
Synonyms Necrostatin-1;
Formula C13H13N3OS M. Wt 259.33
  • Biological Activity
Description Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade.
Pathways Apoptosis Pathway Others Pathway 
Targets Autophagy RIP 

Structure

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