Dorsomorphin

  • Chemical Properties
CAS No. 866405-64-3 Cat. No. BCP06649
Name Dorsomorphin
Synonyms BML-275; BML275;
Formula C24H25N5O M. Wt 399.49
  • Biological Activity
Description Dorsomorphin is a selective inhibitor of Bone morphogenetic protein (BMP) signaling. It has been found to inhibit BMP signals required for embryogenesis and promoted significant neural differentiation from human pluripotent stem cell (hPSC) lines. Dorsomorphin also acts as a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase); Ki = 109 nM in the presence of 5 μM ATP and the absence of AMP).
Related Products 1219168-18-9(Dorsomorphin dihydrochloride)
Pathways PI3K/Akt/mTOR Epigenetics 
Targets AMPK 

Structure

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