TAK-733

  • Chemical Properties
CAS No. 1035555-63-5 Cat. No. BCP06625
Name TAK-733
Synonyms TAK733;TAK 733;REC-4881;REC 4881;REC4881;
Formula C17H15F2IN4O4 M. Wt 504.23
  • Biological Activity
Description TAK-733 is highly potent and selective MEK allosteric site inhibitor with IC50 of 3.2 nM. TAK-733 shows potent enzymatic and cell activity with an EC50 of 1.9 nM against ERK phosphorylation in cells.
Pathways MAPK Pathway 
Targets MEK/ERK 

Structure

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