莫西普利盐酸盐
| CAS号 | 82586-52-5 | 货号 | BCP21379 |
| 中文名 | 莫西普利盐酸盐 | ||
| 英文名 | Moexipril hydrochloride | ||
| 中文别名 | |||
| 英文别名 | Moexipril HCL; RS 10085; RS-10085; RS10085; SPM-925; SPM 925; SPM925; CI-925; CI 925; CI925; | ||
| 分子式 | C27H35ClN2O7 | 分子量 | 535.03 |
| 生物活性 | Moexipril Hydrochloride is the hydrochloride salt form of moexipril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexipril hydrochloride is hydrolized into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. Moexipril hydrochloride also directly suppresses renin release. | ||
| 信号通路 | Protease/Metabolic Enzyme Hormone Pathay | ||
| 靶 点 | RAAS/ACE | ||
结构式
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