MK-8033

  • Chemical Properties
CAS No. 1001917-37-8 Cat. No. BCP21388
Name MK-8033
Synonyms MK8033;MK 8033;
Formula C25H21N5O3S M. Wt 471.53
  • Biological Activity
Description MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre- and post-treatment biopsies to evaluate for relevant molecular signatures.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets c Met 

Structure

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