MK-8033
CAS No. | 1001917-37-8 | Cat. No. | BCP21388 |
Name | MK-8033 | ||
Synonyms | MK8033;MK 8033; | ||
Formula | C25H21N5O3S | M. Wt | 471.53 |
Description | MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre- and post-treatment biopsies to evaluate for relevant molecular signatures. | ||
Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
Targets | c Met |
Structure
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