Amsilarotene
| CAS No. | 125973-56-0 | Cat. No. | BCP06502 |
| Name | Amsilarotene | ||
| Synonyms | TAC-101;TAC101;TAC 101;AM 555S;AM-555S; | ||
| Formula | C20H27NO3Si2 | M. Wt | 385.6 |
| Description | Amsilarotene ( TAC-101) is a retinobenzoic acid with potential antineoplastic activity. TAC-101 inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. This agent also causes a cytotoxic decline in cyclin A and thymidylate synthase expression. | ||
| Pathways | Others Pathway | ||
| Targets | Others | ||
Structure
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