DY131

  • Chemical Properties
CAS No. 95167-41-2 Cat. No. BCP06497
Name DY131
Synonyms DY-131;DY 131;GSK 9089;GSK-9089;GSK9089;
Formula C18H21N3O2 M. Wt 311.38
  • Biological Activity
Description DY131 inhibited the growth of the ERα-positive endometrial cancer cells but promoted that of the ERα-negative cancer cells. DY131 had no effect on the structurally related receptors ERRα or the estrogen receptors alpha and beta (ERalpha/beta). DY131 appears to inhibit Smo signaling through a common binding site shared by previously reported Smo agonists and antagonists.
Pathways Hormone Pathay 
Targets Estrogen Receptor 

Structure

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