TMC647055
| CAS No. | 1204416-97-6 | Cat. No. | BCP06459 |
| Name | TMC647055 | ||
| Synonyms | TMC 647055;TMC-647055; | ||
| Formula | C32H38N4O6S | M. Wt | 606.73 |
| Description | TMC647055 is a potent HCV NS5B polymerase inhibitor potentially for the treatment of HCV infection. TMC647055 has nanomolar cellular potency (EC(50) of 82 nM) with minimal associated cell toxicity (CC(50)>20 μM) and promising pharmacokinetic profiles in rats and dogs. TMC647055 showed promising in vitro biochemical, kinetic, and virological profile that is currently undergoing clinical evaluation. TMC647055 is currently being evaluated in the clinic. | ||
| Pathways | Protease/Metabolic Enzyme Microbiology/Virology | ||
| Targets | HCV Protease HCV | ||
Structure
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