ZM 306416
| CAS No. | 690206-97-4 | Cat. No. | BCP06445 |
| Name | ZM 306416 | ||
| Synonyms | CB 676475;ZM-306416;ZM306416;CB-676475;CB676475; | ||
| Formula | C16H13ClFN3O2 | M. Wt | 333.74 |
| Description | in vitro: 306416 was found to be very potent toward the EGFR kinase with an IC50 value lower than 10 nM, reaching our assay detection limit and confirming our result using the EGFRB assay. ZM-306416 exhibited inhibitory activity across all three kinases of the panel, yielding IC50 values of 0.33±0.08 μM for SRC, 0.33±0.04 μM for VEGFR1, and 1.3±0.2 μM for ABL kinases. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VEGFR | ||
Structure
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