GW9662
| CAS No. | 22978-25-2 | Cat. No. | BCP06354 |
| Name | GW9662 | ||
| Synonyms | GW 9662;GW-9662; | ||
| Formula | C13H9N2O3Cl | M. Wt | 276.67 |
| Description | GW 9662 is a selective irreversible PPARγ antagonist (IC50 values are 3.3, 32 and 2000 nM for PPARγ, PPARα and PPARδ respectively). Blocks the inhibition of osteoclast formation induced by IL-4 in the low micromolar range (1-2 μM), therefore is more potent than BADGE. Anticancer, inhibits growth of human mammary tumor cell lines. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | PPAR | ||
Structure
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