SL 0101-1
| CAS No. | 77307-50-7 | Cat. No. | BCP21457 |
| Name | SL 0101-1 | ||
| Synonyms | SL0101; SL0101; SL 0101; | ||
| Formula | C25H24O12 | M. Wt | 516.45 |
| Description | SL0101, a kaempferol glycoside, isolated from the tropical plant F. refracta, is a cell-permeable, selective, reversible, ATP-competitive p90 Ribosomal S6 Kinase (RSK) inhibitor, with an IC50 of 89 nM. Shows proliferation inhibition in human breast cancer cell line MCF-7 and produces a cell cycle block in G1 phase. | ||
| Pathways | PI3K/Akt/mTOR MAPK Pathway | ||
| Targets | RSK | ||
Structure
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