Icotinib Hydrochloride
| CAS No. | 1204313-51-8 | Cat. No. | BCP06306 |
| Name | Icotinib Hydrochloride | ||
| Synonyms | Icotinib HCl;BPI2009; BPI 2009; BPI-2009;BPI-2009H; | ||
| Formula | C22H21N3O4.HCl | M. Wt | 427.89 |
| Description | Icotinib Hydrochloride is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types. | ||
| Related Products | 610798-31-7（Icotinib） | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR | ||
Structure
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