Loxiglumide
| CAS No. | 107097-80-3 | Cat. No. | BCP21488 |
| Name | Loxiglumide | ||
| Synonyms | CR-1505; CR 1505; CR1505; | ||
| Formula | C21H30Cl2N2O5 | M. Wt | 461.38 |
| Description | Loxiglumide is a potent, orally active, and selective CCK-A receptor antagonist which stimulates calorie intake and hunger feelings in humans. Loxiglumide inhibits pancreatic secretion of digestive enzymes, and also blocks CCK-induced gastric secretions and emptying. Intravenous administration of loxiglumide antagonized the CCK-induced reduction of gastric emptying in rats, acceleration of intestinal transport in mice, increase in ileal motility in rabbits, gallbladder contraction in guinea pigs and acceleration of gallbladder emptying in mice. | ||
| Pathways | GPCR/G Protein | ||
| Targets | Cholecystokinin Receptor | ||
Structure
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