Rubitecan
| CAS No. | 91421-42-0 | Cat. No. | BCP06207 |
| Name | Rubitecan | ||
| Synonyms | RFS 2000; RFS-2000; RFS2000;9-Nitrocamptothecin;9-NC;9 NC;9NC; 9-nitro-20(S)-camptothecin; | ||
| Formula | C20H15N3O6 | M. Wt | 393.35 |
| Description | Rubitecan is a pyranoindolizinoquinoline that is camptothecin in which the hydrogen at position 9 has been replaced by a nitro group. It is a prodrug for 9-aminocamptothecin. It has a role as an antineoplastic agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor and a prodrug. It is a pyranoindolizinoquinoline, a C-nitro compound, a semisynthetic derivative, a tertiary alcohol and a delta-lactone. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | Topoisomerase | ||
Structure
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