JK184
| CAS No. | 315703-52-7 | Cat. No. | BCP21568 |
| Name | JK184 | ||
| Synonyms | JK-184; JK 184; | ||
| Formula | C19H18N4OS | M. Wt | 350.44 |
| Description | JK-184 is a potent downstream hedgehog (Hh) signaling inhibitor that prevents Gli-dependent transcriptional activity (IC50 = 30 nM). JK184 can specially inhibit Gli in the Hedgehog (Hh) pathway, which showed great promise for cancer therapeutics. | ||
| Pathways | Wnt/Stem Cell | ||
| Targets | Hedgehog Gli | ||
Structure
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