美托拉腙
| CAS号 | 17560-51-9 | 货号 | BCP21574 |
| 中文名 | 美托拉腙 | ||
| 英文名 | Metolazone | ||
| 中文别名 | |||
| 英文别名 | Zaroxolyn; | ||
| 分子式 | C16H16ClN3O3S | 分子量 | 365.83 |
| 生物活性 | Metolazone is a thiazide-like diuretic. It is primarily used to treat congestive heart failure and high blood pressure. Metolazone indirectly decreases the amount of water reabsorbed into the bloodstream by the kidney, so that blood volume decreases and urine volume increases. This lowers blood pressure and prevents excess fluid accumulation in heart failure. Metolazone is sometimes used together with loop diuretics such as furosemide or bumetanide, but these highly effective combinations can lead to dehydration and electrolyte abnormalities. | ||
| 信号通路 | Protease/Metabolic Enzyme | ||
| 靶 点 | Thrombin | ||
结构式
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