Relugolix

  • Chemical Properties
CAS No. 737789-87-6 Cat. No. BCP21587
Name Relugolix
Synonyms TAK385; TAK-385;TAK-385;
Formula C29H27F2N7O5S M. Wt 623.63
  • Biological Activity
Description elugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH) receptor antagonist administered orally. By preventing LH-RH from binding with the LH-RH receptor in the anterior pituitary gland and suppressing the secretion of luteinizing hormone (LH) and follicle stimulation hormone (FSH) from the anterior pituitary gland, TAK-385 controls the effect of LH and FSH on the ovary, reduces the level of estrogen in blood, which is known to be associated with the development of endometriosis and uterine fibroids, and is expected to improve the symptoms of these disorders.
Pathways GPCR/G Protein 
Targets GnRH Receptor 

Structure

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