瑞卢戈利
| CAS号 | 737789-87-6 | 货号 | BCP21587 |
| 中文名 | 瑞卢戈利 | ||
| 英文名 | Relugolix | ||
| 中文别名 | |||
| 英文别名 | TAK385; TAK-385;TAK-385; | ||
| 分子式 | C29H27F2N7O5S | 分子量 | 623.63 |
| 生物活性 | elugolix, also known as TAK-385, is a luteinizing hormone-releasing hormone (LH-RH) receptor antagonist administered orally. By preventing LH-RH from binding with the LH-RH receptor in the anterior pituitary gland and suppressing the secretion of luteinizing hormone (LH) and follicle stimulation hormone (FSH) from the anterior pituitary gland, TAK-385 controls the effect of LH and FSH on the ovary, reduces the level of estrogen in blood, which is known to be associated with the development of endometriosis and uterine fibroids, and is expected to improve the symptoms of these disorders. | ||
| 信号通路 | GPCR/G Protein | ||
| 靶 点 | GnRH Receptor | ||
结构式
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