Semaxinib
| CAS No. | 204005-46-9 | Cat. No. | BCP06068 |
| Name | Semaxinib | ||
| Synonyms | SU5416;SU-5416;SU 5416; | ||
| Formula | C15H14N2O | M. Wt | 238.28 |
| Description | SU5416 went as far as Phase III clinical trials as an anticancer agent, putatively because of its activity as a VEGFR-2 inhibitor. SU5416 has biologic activity in patients with refractory acute myeloid leukemia or myelodysplastic syndromes. SU5416 inhibits tumor vascularization and growth of multiple tumor types. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | VEGFR | ||
Structure
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