GSK-25
CAS No. | 874119-56-9 | Cat. No. | BCP21619 |
Name | GSK-25 | ||
Synonyms | GSK25;GSK 25; | ||
Formula | C24H16Cl2F2N6O | M. Wt | 513.34 |
Description | GSK-25 maintains good selectivity against a panel of 31 kinases, as well as RSK1 and p70S6K (RSK1 IC50 of 398 nM, p70S6K IC50 of 1000nM), and a dramatically improved P450 profile (>2.2 uM at all isozymes tested). | ||
Pathways | PI3K/Akt/mTOR MAPK Pathway | ||
Targets | RSK |
Structure
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