Sofosbuvir

  • Chemical Properties
CAS No. 1190307-88-0 Cat. No. BCP06035
Name Sofosbuvir
Synonyms PSI 7977;PSI-7977;PSI7977; GS7977; GS-7977; GS 7977;
Formula C22H29FN3O9P M. Wt 529.45
  • Biological Activity
Description PSI-7851 is a mixture of two similar molecules, PSI-7976 and PSI-7977, which exist in PSI-7851 as isomers of each other. Once inside a liver cell, both molecules are rapidly converted to the same active triphosphate. Given the ability to more easily manufacture PSI-7977, and potentially advantageous in vitro characteristics, PSI-7977 was selected for further clinical development.
Pathways Microbiology/Virology Cell Cycle/DNA Damage 
Targets DNA/RNA Synthesis HCV 
  • Publications Citing

Structure

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