Dorzolomide hydrochloride

  • Chemical Properties
CAS No. 130693-82-2 Cat. No. BCP21713
Name Dorzolomide hydrochloride
Synonyms Dorzolamide HCl;L 671152;MK-507;L-671152;MK507;L671152;MK 507;
Formula C10H17ClN2O4S3 M. Wt 360.88
  • Biological Activity
Description Dorzolamide is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. This drug, developed by Merck, was the first drug in human therapy (market introduction 1995) which resulted from structure-based drug design. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. The combination of dorzolamide with timolol is marketed under the trade name Cosopt.
Pathways Protease/Metabolic Enzyme 
Targets Carbonic Anhydrase 

Structure

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