维妥色替
| CAS号 | 1009298-59-2 | 货号 | BCP05748 |
| 中文名 | 维妥色替 | ||
| 英文名 | Vistusertib | ||
| 中文别名 | |||
| 英文别名 | AZD 2014; AZD-2014; AZD2014; | ||
| 分子式 | C25H30N6O3 | 分子量 | 462.54 |
| 生物活性 | Vistusertib, also known as AZD2014, is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor AZD2014 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR, a serine/threonine kinase that is upregulated in a variety of tumors, plays an important role downstream in the PI3K/Akt/mTOR signaling pathway. | ||
| 上下游产品 | AZD2014（维妥色替硫酸盐） | ||
| 信号通路 | PI3K/Akt/mTOR | ||
| 靶 点 | mTOR | ||
结构式
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