Ertapenem disodium

CAS No.	153832-38-3	Cat. No.	BCP05751
Name	Ertapenem disodium
Synonyms	Ertapenem Sodium; MK 826; MK-826; MK826; MK-0826; MK 0826; MK0826; L 749345; L749345; L-749345; Invanoz; Invanz;
Formula	C22H23N3Na2O7S	M. Wt	519.48

Description	Ertapenem Sodium is the sodium salt of ertapenem, a 1-beta-methyl carbapenem and a broad-spectrum beta-lactam antibiotic with bactericidal activity. Ertapenem binds to penicillin binding proteins located on the bacterial cell wall, in particular PBPs 2 and 3, thereby inhibiting the final transpeptidation step in the synthesis of peptidoglycan, an essential component of the bacterial cell wall. Inhibition of peptidoglycan synthesis results in weakening and lysis of the cell wall and cell death. Erapenem is resistant to hydrolysis by a variety of beta-lactamases, including penicillinases, cephalosporinases and extended-spectrum beta-lactamases.
Pathways	Microbiology/Virology
Targets	Antibiotic

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