Lucitanib

  • Chemical Properties
CAS No. 1058137-23-7 Cat. No. BCP05747
Name Lucitanib
Synonyms E-3810;E 3810;
Formula C26H25N3O4 M. Wt 443.49
  • Biological Activity
Description VEGFR/FGFR dual kinase inhibitor E-3810 inhibits VEGFR-1, -2, -3 and FGFR-1, -2 kinases in the nM range, which may result in the inhibition of tumor angiogenesis and tumor cell proliferation, and the induction of tumor cell death. Both VEGFRs and FGFRs belong to the family of receptor tyrosine kinases that may be upregulated in various tumor cell types.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets VEGFR FGFR 

Structure

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