Raloxifene hydrochloride
CAS No. | 82640-04-8 | Cat. No. | BCP05713 |
Name | Raloxifene hydrochloride | ||
Synonyms | LY-139481 HCl; LY139481 HCl; LY 139481 HCl;Raloxifene HCl; | ||
Formula | C28H27NO4S.HCl;C28H28ClNO4S | M. Wt | 510.04 |
Description | Raloxifene Hcl(LY156758 Hcl) is a second generation selective estrogen receptor antagonist.Raloxifene, also known as LY-139481, is a selective benzothiophene estrogen receptor modulator (SERM). Raloxifene binds to estrogen receptors (ER) as a mixed estrogen agonist/antagonist; it displays both an ER-alpha-selective partial agonist/antagonist effect and a pure ER-beta-selective antagonist effect. This agent functions as an estrogen agonist in some tissues (bones, lipid metabolism) and as an estrogen antagonist in others (endometrium and breasts), with the potential for producing some of estrogen's beneficial effects without producing its adverse effects. | ||
Pathways | Hormone Pathay | ||
Targets | Estrogen Receptor |
Structure
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