INCB 3284
CAS No. | 887401-93-6 | Cat. No. | BCP05717 |
Name | INCB 3284 | ||
Synonyms | INCB 3284 dimesylate;INCB-3284;INCB3284; | ||
Formula | C26H31F3N4O4.2CH4O3S | M. Wt | 712.76 |
Description | INCB 3284 exhibits potenct antagonism against monocyte chemoattractant molecule binding to hCCR2 and chemotaxis activity (IC50 values are 3.7 and 4.7 nM respectively). INCB 3284 also displays weak hERG activity; inhibits the hERG potassium current (IC50 = 84μM). | ||
Pathways | GPCR/G Protein | ||
Targets | CCR |
Structure
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