Bitopertin

  • Chemical Properties
CAS No. 845614-11-1 Cat. No. BCP05690
Name Bitopertin
Synonyms Paliflutine;RG1678; RO4917838; RG-1678; RG 1678; RO-4917838; RO 4917838;
Formula C21H20F7N3O4S M. Wt 543.45
  • Biological Activity
Description Bitopertin, also known as Paliflutine and RG-1678, is a glycine reuptake inhibitor which was under development as an adjunct to antipsychotics for the treatment of persistent negative symptoms or suboptimally-controlled positive symptoms associated with schizophrenia. Bitopertin-mediated glycine reuptake inhibition may represent a novel treatment option for schizophrenia, with the potential to address negative symptoms.
Pathways Ion Channel/Membrane Transporter 
Targets GlyT 

Structure

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